Clinical Studies

Treatment of Hypertrophic and Keloid Scars with Silastic Gel Sheeting
Dockery GL, Nilson RZ Journal Foot and Ankle Surgery 1994 Mar-Apr; 33 2: 110

"An evaluation of the results of treatment of both fresh and long-standing hypertrophic and keloid scars on the lower extremities using topical SILASTIC Gel Sheeting was performed in 94 patients ranging in age from 11 to 73 years. In the total of 94 patients, there were 80 with true hypertrophic scars. Of this group, 74 patients (92.5%) were greatly improved with treatment, five patients (6.25%) were somewhat improved, and one patient (1.25%) was not improved . The remaining 14 patients in the study had true keloid scars, and their results were poorer with five patients (35.7%) greatly improved, five patients (35.7%) somewhat improved, and four patients (28.6%) showing no improvement. When all patients were totalled together, there were 79 patients (84%) greatly improved, 10 patients (11%) somewhat improved, and only five patients (5%) with no improvements. Overall, the success rate (somewhat improved to greatly improved) for the treatment of hypertrophic and keloid scars is high (95%) ."

Topical Silicone Gel Sheeting in the Treatment of Hypertrophic Scars and Keloids. A Dermatologic Experience
Gold MH J. Dermatology Surgical Oncology 1993; 19: 912-916

"Topical silicone gel sheeting has been used successfully in the management of hypertrophic and keloid scars resulting from thermal burn wounds.

METHODS: An open-labelled approach using the silicone gel sheets was performed using hypertrophic and keloid scars secondary to surgical procedures or traumatic insults.

RESULTS: The silicone gel sheets resulted in moderate improvement in scar thickness, scar color and was noted to be effective to some degree in all tested. The material was easy to use and painless.

CONCLUSION: Topical silicone gel sheeting is an effective method for the treatment of hypertrophic and keloid scars and may be considered useful in the treatment of these difficult cutaneous lesions."

Topical Treatments for Hypertrophic Scars
Zurada AB, Kriegel D, Davis I, Journal of the American Academy of Dermatology December 2006: 55: 6

"The therapeutic effect of topical gel sheeting on pre-existing hypertrophic scars is well documented. A number of controlled studies exist. For example, in a controlled trial of 20 patients who had either evolving hypertrophic scars or keloids, silicone gel sheeting stopped the development of and softened evolving hypertrophic lesions in 85% of cases. Silicone gel sheeting has also been shown to significantly improve elasticity of old scars between 1 and 6 months after treatment when compared with untreated scars."

Silicone Gel in the Treatment of Keloid Scars
Mercer NSG British Journal Plastic Surgery 1989, 42: 83-87

"The clinical effect of 0.6 mm thick silicone occlusive sheeting (SOS) applied over 32 hypertrophic and keloid scars was investigated. 88% of scars treated and followed up on showed distinct improvement. These results compared favorably to those published in other series."

Topical Treatments for Hypertrophic Scars
Zurada AB, Kriegel D, Davis I, Journal of the American Academy of Dermatology December 2006: 55: 6

Silicone Gel: A New Treatment for Burn Scars & Contractures.
Perkins K, Davey RB, Wallis KA Burns 1982; 9: 201-204

Treating Hypertrophic Scars with Silicone Gel. A Preliminary Report of a Trial of Silastic Gel in the Treatment of Patients with Hypertrophic Burn Scars.
Carney SA, Cason CG, Gowas JP Journal of Wound Care 1993; 2: 197-198

Evidence That Use of a Silicone Sheet Increases Range of Motion Over Burn Wound Contractures
Wessling N., Ehleben CM, Chapman V., May SR & Still JM Journal of Burn Care & Rehabilitation 1985/6 p503-5

Silicone Gel Appears Inexplicably to Flatten and Lighten Hypertrophic Scars from Burns
Kirn TF JAMA ( United States) May 12, 1989, 261 (18) p2600

Non-Pressure Treatment of Hypertrophic Scars
Quinn KJ, Evans JH, Courtney JM, Gaylor JDS, Reid Wh Burns 1985; 12: 102-108

Oncologic Applications for Silicone Gel Sheets in Soft Tissue Contractures
Burkhardt A, Weitz J American Journal of Occupational Therapy, May 1991, 45: 460-2

Static-Electric Field Induction by a Silicone Cushion for the Treatment of Hypertrophic and Keloid Scars
Hirshowitz B, Lindenbaum E, Har-Shai Y, Feitelberg L, Tendler M, Katz K Plastic and Reconstructive Surgery, April 1998 p: 1173-1183

Silicone Gel in the Treatment of Keloid Scars
Mercer NSG British Journal Plastic Surgery 1989, 42: 83-87

Silicone Gel Scar Treatment
Quinn KJ Controlled Therapeutics (Scotland) Ltd., East Kilbridge Burns Include Therm Inj (England) OCT 1987, 13 SUPPL S33 40

Topical Silicone Gel Sheeting in the Treatment of Hypertrophic Scars and Keloids. A Dermatologic Experience
Gold MH J. Dermatology Surgical Oncology 1993; 19: 912-916

Treatment of Hypertrophic and Keloid Scars with Silastic Gel Sheeting
Dockery GL, Nilson RZ Journal Foot and Ankle Surgery 1994 Mar-Apr; 33 2: 110

Skin Disorders in Black Children
Laude TA Current Opinion Pediatrics, 1996 Aug 8 4: 381-385

Effectiveness of Silastic Sheet Coverage in the Treatment of a Keloid Scar:
Ohmori S. Aesthetic Plastic Surgery 1988 ; 12: 95-99

Topical Silicone Gel: A New Treatment for Hypertrophic Scars
Ahn ST, Monafo WW, Mustoe TA Surgery 1989 Oct, 106 4: 781-786

Topical Silicone Gel for the Prevention and Treatment of Hypertrophic Scars
Ahn ST, Monafo WW, Mustoe TA, Arch Surgery 1991, 126: 499-504

Silicone Gel in the Treatment of Keloids
Murdoch ME, Salisbury JA, Gibson JR ACTA Derm. Venereol 1990, 70/2 (181-183)

Treatment of Scars and Keloids with a Cream Containing Silicone Oil
Sawada Y, Sone K. British Journal of Plastic Surgery 1990, 43/6 (683-688)

The Use of Silicone Gel in the Control of Hypertrophic Scarring
McNee J. Physiotherapy 1990, 76/4 ( 194-197)

Hypertrophic Sternal Scars: Silicone Gel Sheet versus Kenalog Injection Treatment
Sproat, JE, Dalcin A, Weitauer N, Roberts RS Plastic and Reconstructive Surgery, 1991 90: 988-992

Silicone Occlusive Sheeting (S0S) in the Management of Hypertrophic
Scarring, Including the Possible Mode of Action of Silicone Hirshowitz, B. et al (1993) European Journal of Plastic Surgery, 16:5-9

Sense and Nonsense of Scar Creams and Gels
Van den helder CJM, Hage JJ Anesth Plastic Surgery 1994; 18: 307-313